DEVELOPMENT AND TESTING OF TREATMENT REGIMENS FOR FIBRINOUS MASTITIS USING NEW THERAPEUTIC AGENTS
Keywords:
udder, mastitis, milk, diagnostics, treatment, fish oilAbstract
Mastitis, or inflammation of the mammary gland, is a common pathology in dairy cows that has significant economic importance. The economic losses caused by mastitis include reduced milk productivity, deterioration of milk quality, the forced culling of cows with chronic forms of the disease, and the financial costs associated with treatment. The development of mastitis can be triggered by any exogenous or endogenous factor that disrupts the barrier function of the mammary gland. Despite the considerable scientific and practical attention given to the problem of mastitis, the economic damage it causes continues to increase. Therefore, the study of etiological factors, diagnostic methods, treatment strategies, and preventive measures for mastitis remains one of the priority tasks in modern dairy farming.
This article presents the results of mastitis therapy in cattle using the “NitRyb” preparation. The developed formulation combines Nitox and fish oil. In its emulsion form, fish oil is dispersed into smaller particles compared to other lipids, which provides higher bioavailability. Experimental data indicate more effective penetration of the preparation through the pores of cell membranes and an accelerated oxidation process. Due to deep absorption and penetration into inflamed tissues, the drug exhibits therapeutic activity within a short period after administration.
Nitox is a slightly viscous liquid that varies in color from light to dark brown. Its active component, oxytetracycline, possesses a bacteriostatic effect by inhibiting protein synthesis in most gram-positive and gram-negative microorganisms.
The “NitRyb” preparation is used for the first time in veterinary practice and is characterized by analgesic, vasoconstrictive, antiseptic, and anti-inflammatory properties. In addition, it enhances immunological functions, increases the body’s resistance to pathogenic and toxic factors, and stimulates tissue regeneration processes.
Downloads
Downloads
Published
Issue
Section
License
Copyright (c) 2025 The editorial staff of the journal follows the copyright law of the Republic of Kazakhstan and relevant international agreements. The authors retain their copyright and provide the journal «Bulletin of Shakarim University. Series of Historical Sciences» right of first publication of the manuscript. The author has the right to copy and distribute the material in any medium and in any format, subject to appropriate reference to the journal. Readers and users can freely copy, distribute and adapt the material, provided that the author of the work is indicated and a link to this journal is provided. Copyright presupposes the integrity and responsibility of each co-author who made a significant contribution to the writing of the article. The author has the right to store his publications in an institutional or other repository of his choice, provided he provides the appropriate link to the journal’s website.
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Copyright presupposes the integrity and responsibility of each co-author who made a significant contribution to the writing of the article.
The author has the right to store his publications in an institutional or other repository of his choice, provided he provides the appropriate link to the journal’s website.
