BLOOD CHARACTERISTICS IN SHEEP WITH VARIOUS FORMS OF DERMATITIS

Abstract

ANNOTATION

This study provides a comprehensive analysis of hematological and biochemical blood parameters in sheep with dermatitis of varying severity and etiology.

The data obtained demonstrate a clear relationship between the severity of skin lesions and changes in blood composition. Hematological parameters indicate a decrease in hematocrit and hemoglobin levels with increasing severity of dermatitis, which may indicate a violation of erythropoiesis or suppression of bone marrow function in conditions of inflammation and chronic intoxication. At the same time, there is an increase in erythrocyte sedimentation rate (ESR), leukocyte count, neutrophils, and eosinophils, reflecting activation of the immune response and the presence of a systemic inflammatory process. Signs of thrombocytopenia have been identified in severe cases of the disease, which is associated with the redistribution of blood elements and toxic effects.

Biochemical blood analysis shows a tendency toward increased levels of bilirubin, liver enzymes (ALT, AST), creatinine, and alkaline phosphatase as dermatitis progresses, indicating the involvement of the liver and kidneys in the pathological process and the development of toxic damage. An increase in total protein and globulins indicates enhanced synthesis of acute phase proteins and activation of the immune system.

Thus, changes in hematological and biochemical blood parameters serve as important diagnostic and prognostic markers of the severity of dermatitis in sheep. Their comprehensive study allows assessing the general condition of the animals, identifying pathophysiological disorders, and contributes to the selection of adequate therapeutic measures. The results of the study emphasize the importance of blood monitoring in skin diseases of sheep of various etiologies.