CREATION AND IMPLEMENTATION OF MODERN METHODS OF TREATMENT OF COCCIDIOSIS-ESOPHAGOSTOMOSIS INVASION IN FARMS "ULAN", "YERLAN"

Abstract

ANNOTATION

Parasitic diseases of sheep reduce  production potential, also lead to  decrease  economic efficiency  industry  Republic of Kazakhstan. Therefore, the aim work was to study the dynamics  development clinical form of manifestation of associated eimeriosis-esophagostomous invasion, as well as the concomitant immunodeficiency state body of lambs during experimental infection and the effectiveness of complex methods of treatment of sheep with associated invasions. During the work, helminthioscopic studies were used, followed by the calculation of the indicators extent  intensity of invasion, as well hematological studies with determination of subpopulations of T and B lymphocytes. As result conducted studies, it was found that during experimental infection of lambs with invasive eimeria and esophagostomes, eimeria oocysts began to be released with feces on day 14, while esophagostome eggs appeared only on day 24. Due to the more active development of protozoa, the main symptoms associated invasion were signs characteristic  acute eimeriosis. With the development  disease, the intensity of invasion for both pathogens showed positive dynamics in all animals. At the same time, signs immunosuppressive state were observed in animals with the development of invasion. A decrease  total number of leukocytes (up to 25%), as well as T and B lymphocytes, which indicates a decrease humoral function of the immune system. With the development of the disease on day 24, there is an increase in the level of T-lymphocytes (by 0.8%) due to an increase in T-helpers (by 2.0%).